D-Pinitol

How You May Benefit:

Promote stamina
Increase prolonged energy output by improving glucose metabolism
Increase fat metabolism
Aid in weight management by mimicking insulin
Assist energy storage
Improve glucose metabolism and help increase cellular energy
Prolong lifespan
Potentially help lower triglycerides in patients with elevated insulin resistance

Overview

Recent research has found this form of the vitamin B inositol may have profound insulin-like properties, which may explain its long use in traditional healing medicine for numerous diabetic-associated conditions. D-Pinitol has now become one of the better studied insulin mimickers in the supplement industry and is proving to be an excellent aid in improving glucose metabolism. Also noteworthy, it's been shown to help enhance the uptake of creatine without the use of high-calorie simple carbohydrates.

Usage

Amount: When used to enhance creatine uptake, clinical studies found between 1 and 2 grams daily initially and then dropping to 500 mg to 1 gram daily to be effective.

Timing: It's best to take D-pinitol with carbohydrate-rich foods or other specific supplements; namely, creatine, as recommended.

Efficient glucose metabolism can improve the storage of glycogen, which ultimately improves endurance, athletic performance, muscle volume, and post-workout recovery. Pinitol, then, is attractive because it may help improve glucose metabolism.

Safety Information

Known drug interactions:
Although none are specifically indicated, consult with your practitioner if you suffer from any ailments involving insulin function and are using medication for such.

Toxicity:
There have been significant pre-clinical safety studies that have shown D-pinitol is safe and nontoxic even at high levels.

Bans and Restrictions:
None reported.

References

The data support the view that D-pinitol can exert an insulin-like effect to improve glycaemic control in hypoinsulinaemic STZ-diabetic mice. D-pinitol may act via a post-receptor pathway of insulin-action affecting glucose uptake.

British Journal of Pharmacology 130 (2000) : 1944-8.

Greenwood, M., et al., "D-Pinitol Augments Whole Body Creatine Retention in Man," ASEP 4.4 (2001) : 41-7.

Narayanan, C., "Pinitol—A New Anti-Diabetic Compound from the Leaves of Bougainvillea," Current Science 56.3 (1987) : 139-41.

Ostlund, R., and Sherman, W., "Measurement of D-chiro-Inositol in Clinical Studies," Diabetes Care 18.7 (1995) : 1074-5.

Rasmussen, C., et al., "Influence of D-Pinitol on Whole Body Creatine Retention," www.acsm-msse-org, abstract 1147.

www.humaneticscorp.com
Humanetics is the exclusive worldwide licensee of the following patents:

U.S. Patent Number: 5,550,166
U.S. Patent Number: 5,827,896

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