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Tyrosine

How You May Benefit:
  • Increase mental focus
    Increase mental clarity as the direct precursor to the neurotransmitters epinephrine, norepinephrine, and dopamine
  • Control stress
    Relieve stress, anxiety, and mild depression as the direct precursor to the neurotransmitters epinephrine, norepinephrine, and dopamine
  • Reduce mental fatigue
    Enhance mood and reduce fatigue by blocking the absorption of the amino acid tryptophan
  • Stimulate growth hormone
    Potentially stimulate the secretion of growth hormone

Overview

As a precursor to several important neurotransmitters, tyrosine appears to have potent stimulating effects on the brain and has been shown to help individuals perform better mentally—aiding focus and alertness as well as inhibiting feelings of stress and fatigue.

Usage

Amount: Research suggests one to three grams a day as the most effective amount.

Timing: Tyrosine should always be taken on an empty stomach for optimal absorption. And if taken 30 minutes before a workout, tyrosine may increase intensity and focus in the gym.

Note: Taking tyrosine a half hour before eating is reportedly effective for stimulating energy and mood and/or suppressing appetite.

Known as the "antidepressant" amino acid, tyrosine is most commonly used to help lift mood and mental functioning. Some individuals report it's especially effective for helping reduce stress and mental burnout. Strength athletes have also found it may help boost strength by improving the mind-body connection.

Safety Information

Safety:
Tyrosine is not recommended for people with high blood pressure or skin cancer.

Known drug interactions:
If you are currently using MAO inhibitors or other antidepressant drugs, tyrosine is not recommended as this combination may raise blood pressure.

Toxicity:
None known.

Bans and Restrictions:
None reported.

References

Banderet, L.E., and Lieberman, H.R., "Treatment with Tyrosine, a Neurotransmitter Precursor, Reduces Environmental Stress in Humans," Brain Res Bull 22 (1989) : 759-62.

Deijen, J.B., et al., "Tyrosine Improves Cognitive Performance and Reduces Blood Pressure in Cadets After One week of a Combat Training Course," Brain Res Bull 48.2 (1999) : 203-9.

Gelenberg, A.J., et al., "Tyrosine for Depression," J Psychiatr Res 17.2 (1982-83) : 175-80.

Gelenberg, A.J., and Gibson, C.J., "Tyrosine for the Treatment of Depression," Nutr Health 3.3 (1984) : 163-73.

van Praag, H.M., "In Search of the Mode of Action of Antidepressants: 5-HTP/Tyrosine Mixtures in Depression," Adv Biochem Psychopharmacol 39 (1984) : 301-14.


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