Overview

The product of years of intense research, 7-Keto™ is a new breed of supplement—one engineered for specific results. Its ability to promote safe fat loss without the buzz of stimulants is a breakthrough in weight-loss supplements. It has also shown anti-aging actions and shows promise for boosting the immune system and enhancing memory.

The Full Story

Usage

Amount: Interestingly, because of the high cost to produce 7-Keto, most manufacturers suggest taking 25 mg per day. However, according to the most recent studies, 50 to 100 mg of 7-Keto taken twice daily (for 100 to 200 mg per day) was found to be most effective for weight loss.

Timing: Research shows the ideal time to consume 7-Keto is once in the morning and again later in the afternoon, before meals.

7-Keto has been shown to help our bodies burn more fat, faster, without the stimulating effects most thermogenics impart. This can be a real benefit for those who are sensitive to stimulants and those who wish to supplement for longer periods. As an added bonus, 7-Keto also supports the immune system and helps prevent age-related health complications.

Questions and Answers

Q.	What does the research on 7-Keto show?
A.	7-Keto's potential to promote weight loss in overweight individuals has been investigated in a double-blind study. Participants in the study were advised to exercise 3 times per week for 45 minutes and to eat an 1,800-calorie per day diet. Each individual was given either a placebo or 100 mg of 7-Keto twice daily. After 8 weeks, those receiving 7-Keto had lost an average of 6.34 lbs compared with 2.13 lbs in the placebo group (a statistically significant difference). In addition, bodyfat decreased by 1.8% in the 7-Keto group, compared with only 0.57% in the placebo group. The increased weight loss in the 7-Keto group was associated with a significant increase in levels of T3 (a thyroid hormone that plays a major role in determining a person's metabolic rate), although the levels of T3 did not exceed the normal range. Tests in animals and test tubes have been performed in the areas of immune modulation, memory enhancement, and thermogenesis (the process the body uses to convert stored calories into energy).
Q.	Could any other supplements make 7-Keto even more effective?
A.	None have been reported as of yet.
Q.	What's the most common amount of 7-Keto used to achieve optimal results?
A.	Interestingly, because of the high cost to produce 7-Keto, manufacturers suggest taking 25 to 50 mg per day. However, according to the most recent studies, 100 mg of 7-Keto taken twice daily (for 200 mg per day) was found to be most effective for weight loss.
Q.	Can too much 7-Keto cause any side effects—is it safe?
A.	Clinical studies show that 7-Keto is quite safe, and no toxicity has been observed. A safety study in humans has shown that 7-Keto did not raise estrogen or testosterone levels or produce any other negative effects at levels up to 200 mg per day for 8 weeks. Short-term animal studies also revealed no adverse effects with large amounts of 7-Keto.
Q.	Should anyone avoid 7-Keto?
A.	The increase in T3 levels resulting from taking 7-Keto could, in theory, produce adverse effects on those with existing heart or thyroid problems. For these reasons, people wishing to take 7-Keto, particularly those who have a heart or thyroid disorder, or are taking thyroid hormone, should consult a physician before use.

Safety Information

Safety:
If you are pregnant or lactating, 7-Keto is not recommended.

Toxicity:
None known.

Bans and Restrictions:
None reported.

References

Baulieu, E.E., and Robel, P., "Dehydroepiandrosterone (DHEA) and Dehydroepiandrosterone Sulfate (DHEAS) as Neuroactive Neurosteroids (comment)," Proc Natl Acad Sci U S A 95.8 (1998) : 4089-91.

Bobyleva, V., et al., "The Effects of the Ergosteroid 7-Oxo-Dehydroepiandrosterone on Mitochondrial Membrane Potential: Possible Relationship to Thermogenesis," Arch Biochem Biophys 341.1 (1997) : 122-8.

Colker, C., et al., "Double-Blind, Placebo-Controlled, Randomized Clinical Trail Evaluating the Effects of Exercise Plus 3-Acetyl-7-oxo-dehydroepiandrosterone on Body Composition and the Endocrine System in Overweight Adults," J Exer Physiol Online 2.4 (1999).

Davidson, M.H., et al., Clinical Safety and Endocrine Effects of 7-Keto™ DHEA (presented at Experimental Biology '98, San Francisco, CA).

Kalman, D.S., et al., "A Randomized, Double-Blind, Placebo Controlled Study of 3-Acetyl-7-Oxo-Dehydroepiandrosterone in Healthy Overweight Adults," Curr Ther Res 61.7 (2000) : 435-42.

Khorram, O., "DHEA: A Hormone with Multiple Effects," Curr Opin Obstet Gynecol 8.5 (1996) : 351-4.

Kroboth, P.D., et al., "DHEA and DHEA-S: A Review," J Clin Pharmacol 39.4 (1999) : 327-48.

Lardy, H., et al., "Ergosteroids. II: Biologically Active Metabolites and Synthetic Derivatives of Dehydroepiandrosterone," Steroids 63.3 (1998) : 158-65.